Directed Self-assembly of Fluorogenic Particles

Professor Donal O'Shea is Head of Department, Pharmaceutical & Medicinal Chemistry, Royal College of Surgeons in Ireland, 2013 - to date.

Research Interests

The central theme of his research lies in the advancement of new strategies for the synthesis and functional assessment of structurally complex molecules. Specific goals include the development of new light activated anti-cancer and anti-microbial agents, the investigation of novel concepts for drug selectivity and the generation of chemical tools to assist in gaining a molecular level insight into biological processes.
His research has its foundations in medicinal organic chemistry and chemical biology with strong collaborative links with biological imaging and medicine.

On-going Research Projects

(Details of on-going Research Projects)

Near-infrared fluorochromes for real-time in vitro and in vivo imaging; tools for chemical biology and fluorescence guided surgery.
A new class of photodynamic therapeutic agent with anti-cancer and anti-bacterial potential.
Innovative methodologies for pharmaceutical synthesis utilizing microflow reactors.
Mixed metal Li/K amides (LiNK chemistry) as new reagents for synthetic chemistry.

Consult RCSI School of pharmacy