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Hypothesis-free NGS data analysis
Evénement
11/01/2018
… and simplifications leading to an important loss of information For instance a major limiting factor is the mapping step where NGS reads are aligned to a reference genome or transcriptome In RNAseq analysis relying on a reference transcriptome amounts to ignoring novel genes … Genome Biol 18 243 … Daniel Gautheret Institute for Integrative Biology of the Cell CNRS UMR 9198 Universite ParisSud invited by LBPA Laboratory will give a lecture …
An international Christmas event
Actualité
22/12/2017
… the event the whole 5 continents were represented proudly Some of them were enrolled in the Secret Santa Game Students were secretly paired No one knew until the very end … The students just finished their first semester of studies at the ENS ParisSaclay now some of them will go back to enjoy some family and friends time for holidays The … Office would like to thank every perso who came to this event and wish everyone a Merry Christmas and Happy New Year 2018 … On Decembre 19 2017 all international …
Diamonds as electron microscopy and integrated microscopy labels
Evénement
28/11/2017
… microscopy combines light and electron microscopy EM With this approach we can label cells and identify them optically but also visualize their membrane structure with EM A major problem with this approach is that conventional optical labels bleach during the sample preparation for EM We found that defect centers in fluorescent nanodiamonds can survive heavy metal staining for EM undisturbed1 As a …
Nano-Optics with fast electrons
Evénement
28/11/2017
… How light behaves and interacts with matter at the nanometer scale is a fascinating subject Indeed at this scale both the electromagnetic field and the … may be subject to confinement This is why the optical properties of nanoobjects will in general depend drastically on their shape size and local environment This is the … or for the excitons in quantum emitters such as Quantum Dots where the confinement now affects the excitons wavefunction The typical sizes at which confinement becomes …
Rac1 signaling nanoclusters
Evénement
27/11/2017
… The plasma membrane of eukaryotic cells is a highly organized surface where hundreds of incoming signals are transduced to the … this myriad of signals is a fundamental question Using single molecule imaging in polarized cells we recently showed that Rac1 a critical membranebound protein … downstream signaling and ensure the fidelity of information transduction Thanks to cell patterning and optogenetics activations we further showed that Rac1 nanoclusters …
sp2 Iminosugars: opportunities for new glycotherapies
Evénement
17/11/2017
… through conjugation or molecular recognition makes sugars essential players in cell life and clearcut sensors of cell state alterations A straight consequence is that any deregulation in carbohydrate metabolism generally …
Michael Grätzel
Portrait
09/10/2017
… A solar energy pioneer Michael Grätzel is a professor at the Ecole Polytechnique … a chemical reaction that produces energy and allows the plant to grow The Grätzel cell now more commonly known as a dyesensitized solar cell or DSSC is composed of two thin …
Cdc42 : polarization of the megakaryocyte and beyond
Evénement
02/10/2017
… Blood platelets are produced by large precursor cells megakaryocytes MKs which extend cytoplasmic protrusions proplatelets PPTs into … remain unknown We have investigated the impact of the actin cytoskeleton dynamics in differentiating MKs We found that Cdc42 plays a crucial role in drivingnbsp polarized formation and structuration of the demarcation …
DHC 2017 : 3 well-known academics rewarded
Actualité
15/09/2017
… their use to generate electricity and fuels from sunlight He invented the Grätzel cell that in turn engendered perovskites photovoltaics cells which are largely commercialized He … before receiving his PhD in Civil Engineering from UC Berkeley He is recognized as a world leader in Simulationbased Engineering Sciences He develops mathematical models …
Synergistic Energy Systems in Cities
Evénement
08/09/2017
… and also increased and more intricate energy demands The increased probability of a larger than expected rise in temperatures and humidity compels us now to consider high gain methods despite their increased engineering complexity …

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